Roche’s Phase 3 Pemphix trial smashes primary endpoint for pemphigus vulgaris

Roche has revealed new Phase 3 data demonstrating that its MabThera/Rituxan (rituximab) therapy Pemphix met its primary endpoint in the treatment of moderate to severe pemphigus vulgaris (PV) in adult patients.

The findings revealed that 40.3% of patients on Roche’s drug achieved complete remission which was sustained for at least 16 weeks without the use of steroids, compared to just 9.5% of those on  mycophenolate mofetil (MMF), achieving the study’s primary endpoint.

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