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Archief voor de categorie ‘Onderzoek’

Antidepressants can be used to treat Alzheimer’s disease

Scientists at the University of Waterloo have discovered that antidepressant medications can be used to treat Alzheimer’s disease. The study, recently published in ACS Chemical Neuroscience, found that selective serotonin uptake inhibitors (SSRI medication) can delay the development and growth of amyloid-beta proteins, which can clump together and form a plaque, contributing to disease symptoms.

Bron: News-Medical.Net Meer lezen »

Roche preps new Kadcyla filings after phase 3 trial win

Giving a HER2-targeting drug before surgery in women with early-stage HER2-positive breast cancer has become routine, but doesn’t always clear away all tumour tissue. Now, Roche has clinical data showing its antibody-drug conjugate Kadcyla offers a second-line of treatment for these patients.

Bron: PMLiVE Meer lezen »

AstraZeneca presents advances in improving treatment options for ovarian, lung cancer patients at ESMO 2018 Congress

AstraZeneca and MedImmune, its global biologics research and development arm, will present 54 abstracts, including eight oral presentations and three late breakers, to the European Society of Medical Oncology (ESMO 2018) Congress in Munich, Germany, 19-23 October.

Bron: Pharma Biz Meer lezen »

Oncolytics Biotech announces publication of positive results for pelareorep in abstract for ESMO 2018 Congress

Oncolytics Biotech Inc, currently developing pelareorep, an intravenously delivered immuno-oncolytic virus turning cold tumours hot, announced publication of an abstract on pelareorep (formerly known as Reolysin) for the European Society for Medical Oncology (ESMO) 2018 Congress, taking place October 19-23 in Munich.

Bron: Pharma Biz Meer lezen »

J&J’s Stelara succeeds in chronic bowel disease study

Johnson & Johnson said on Tuesday its blockbuster drug Stelara was found to be effective in treating a chronic bowel disease in a late-stage trial.

Bron: Reuters Health Meer lezen »

Merck’s HIV therapy Delstrigo meets primary endpoint in phase 3 DRIVE─SHIFT trial

Merck, known as MSD outside the United States and Canada, announced the first presentation of data from the phase 3 DRIVE─SHIFT trial evaluating a switch of medication to Delstrigo, a once─daily fixed─dose combination

Bron: Pharma Biz Meer lezen »

Bewijs voor effectiviteit van behandelingen positief gekleurd

Zorgprofessionals vertrouwen op de medische wetenschap bij het maken van behandelkeuzes. Helaas komt nog niet al het beschikbare bewijs terecht in de wetenschappelijke literatuur. Het is bekend dat met name studies met niet-significante resultaten (negatieve studies) vaak niet worden gepubliceerd. Minder bekend is dat er naast deze publicatiebias ook andere vertekeningen kunnen optreden die de […]

Bron: Meer lezen »

Eli Lilly announces positive results from two phase 3 study of Ultra Rapid Lispro to treat people with type 1 and type 2 diabetes

Readouts from two phase 3 clinical trials demonstrated that Eli Lilly and Company’s Ultra Rapid Lispro (URLi) met the primary efficacy endpoint of non-inferior A1C reduction from baseline compared to Humalog (insulin lispro) and also demonstrated significantly improved post-meal glucose control in people with type 1 and type 2 diabetes.

Bron: Pharma Biz Meer lezen »

Flu drug speeds relief from symptoms in at-risk patients: Roche

Influenza drug baloxavir marboxil significantly sped time to relief for patients highly vulnerable to serious complications, a late-stage clinical trial has shown, Swiss drugmaker Roche said on Thursday.

Bron: Reuters Health Meer lezen »

Eli Lilly’s diabetes treatment meets main goal in two late-stage studies

Eli Lilly and Co said on Tuesday its experimental diabetes treatment was shown to be as effective as the drugmaker’s Humalog medicine in two late-stage studies.

Bron: Reuters Health Meer lezen »

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